… of DN included genetic susceptibility DN gene, increasing … Common genetic variants (single-nucleotide
polymorphisms, … roles in the progression of type 2 diabetes and non-alcoholic …

… Although many genetic variants have been implicated in DN susceptibility, the results are …
The diabetes could be either Type I diabetes mellitus (T1DM) or Type II diabetes mellitus (…

… HMGA2 gene, that has been implicated in activation of the TGF-β1 signalling pathway. Thus,
increased … factors for T2DM have been linked to susceptibility to and development of insulin …

… HMGA2 has been revealed to increase the risk of developing nephropathy in those patients
with type 2 diabetes … Also, our functional analysis suggested that HMGA2 could enhance the …

… The genetic factors are believed to be key predisposing determinants in individual susceptibility
to T2D. Therefore, identifying the predisposing genetic variants could be a crucial step in …

The dysregulated long noncoding RNAs (lncRNAs) are associated with the pathogenesis of
diabetic nephropathy (DN). LncRNA potassium voltage-gated channel subfamily Q member …

… The commonly studied genetic variants in GWAS are single … in RPS12, SASH1, AUH, LIMK2,
MSRB3, SFI1 and HMGA2 to be … greater genetic susceptibility to type 2 diabetes, increased …

… inherited common variants in susceptibility genes were identified. CASC15 was the first …
was associated with increased risk of developing nephropathy in patients with type 2 diabetes. …

… There is increasing evidence for genetic susceptibility to T2DM… of multiple common and rare
variants 66 . Thus, additional … , and 5–28% of patients have nephropathy within the first year …

… In diabetes, PVT1 may also be involved in the susceptibility … antagonizing Let-7 and increased
HMGA2-mediated EMT 81 . … reported in type 2 diabetes patients with diabetic nephropathy …